An excess of food rich in fats and sugars changes the response of the brain to the insulin hormone (even if it does not put on weight).
The effects of garbage food are seen on the brain before even on weight. And five days of “bagroves” are enough with saturated foods of sugars and fats to alter the way the brain responds to the food we ingest. A search published on Nature Metabolism show those that could be The foundations of reduced insulin sensitivity In the brain of people who feed badly: an alteration that can open the doors to obesity and diseases connected to it.
Invisible changes. Stephanie Kullmann, neuroscientist of the University of Tinginga, in Germany, has shown that five days of excesses of particularly unhealthy ultra -prompt foods The brain activity of healthy adult men changeeven if their weight and their body composition are not altered. The response to insulin is modified, the hormone that the pancreas releases to adjust sugars in the blood and which on the brain has the effect of regulating food intake, because it attenuates the feeling of hunger.
Nickebade snacks. In people with obesity The response of the brain to insulin can be weakened. A form of resistance that can alter the way the food is tried by the body. The team recruited 29 male adults and subjected 18 of them to a 5 -day hypercaloric diet, in which each participant received a snack -rich packet of sugars and fats (for example a Mou chocolate bar, brownies and chips in the envelope) for a total of 1,500 kcal to be added to the standard power supply. After a first moment of enthusiasm, the forced diet was cloying and the participants managed to increase the calorie intake only by about 1,200 kcal per day.
From the nose to the brain. The researchers used magnetic resonance imaging to observe the flow of blood to the brain and thus study brain activity first, during and after the week of garbage food. Since the focus of the study was on the response to insulin, to directly study the action of the hormone in the brain the team asked the participants of spray insulin spray in the nose before performing any resonance.
Hyperactivation … After five days of stravizi, the group returning from excess of junk food had an increased activity compared to the control group In three brain regions involved in response to food changes and reward. With patterns similar to those observed in people with obesity and insulin resistance, a phenomenon that can lead to type 2 diabetes.
… loss of sensitivity. A week after the end of the diet, the Reduce group from Junk Food instead showed less brain activity in two regions associated with memory and response to visual signals related to food, such as In a reduced response to insulin “surviving” to the cessation of the unhealthy diet. This insulin resistance in the cerebral region of the hippocampus was present without there being (still) alterations in the peripheral metabolism. The hypothesis is that the changes induced by the diet in the brain can therefore be the premise and the antechamber of the “peripheral” insulin resistance.
Concrete repercussions. Previous studies on people with obesity show that those with brains more sensitive to the action of insulin lose more weight after having changed lifestyle than those with insulin-resistant brains.
