A pill to replace exercise: will it ever exist?

A pill to replace exercise: will it ever exist?

By Dr. Kyle Muller

Nothing has beneficial benefits on the body comparable to those of the exercise. But a molecule produced after a training gives youth to the mice, will it be the solution of the future?

Condense the many benefits of exercise in a pill: will we ever succeed? Probably not, because the effects have had the physical activity on our body are too vast. But a search published on Cell He identified a compound, produced in abundance in training periods, which improves the immune health of the elderly mice and gives them strength. The molecule is called betaine: to avoid misunderstandings, his security – and his any benefits – on man have not yet been tested.

Exercise: Comparisons without comparisons

For many people, sedentary lifestyle is not a choice: for economic, logistical or health reasons, it is not always possible to make the amount of exercise that would be optimal for one’s health. In addition to improving the health of muscles and bones, strengthening the cardiovascular and respiratory system and controlling body weight, training contrasts inflammatory processes, improves immune functions, repairs damaged tissues and keeps the mind shiny.

Betain’s production

A group of scientists from the Chinese Academy of the Sciences of Beijing explored the benefits of physical exercise at a molecular level asking for 13 young healthy men and trained of Limit yourself to very bland levels of physical activity for 45 days. After the forced stop, the volunteers started moving again with a program that included 5 km of running every one or two days. The researchers collected samples of feces and blood both in the 45 days of detention and in the 25 days of the new jogging routine.

A discharge of benefits at a molecular level

The analyzes revealed positive changes at an immune level, intestinal microbiota and fat metabolism: how much it would be enough To convince the laziest to get back in motion. But the most important data concerns Betain’s abundancea molecule whose exercise has induced production in the kidneys. Betain is linked to a protein that promotes aging cells and organs – the TBK1 – and inhibits its production. Exercise strongly increased its concentrations.

The old mice rejuvenates. Man, who knows

Betain -based drinks administered to old mice have strengthened their muscles, inflammation is contrasted, strengthened the immune system and improved the appearance of the skin of animals, which seemed younger than those who had not taken on the molecule additions.

The authors of the study have not yet tested the security and the effects of betaine on man: the partner protein to which he binds suggests that he can contrast the effects of aging, but in order to be able to affirm it with certainty, other groups of scientists would have to be confirmed his role independently.

In the past, other molecules candidates have promised to deliver benefits similar to those of sport in a simple way: many have disappointed expectations, while others are under study.

Kyle Muller
About the author
Dr. Kyle Muller
Dr. Kyle Mueller is a Research Analyst at the Harris County Juvenile Probation Department in Houston, Texas. He earned his Ph.D. in Criminal Justice from Texas State University in 2019, where his dissertation was supervised by Dr. Scott Bowman. Dr. Mueller's research focuses on juvenile justice policies and evidence-based interventions aimed at reducing recidivism among youth offenders. His work has been instrumental in shaping data-driven strategies within the juvenile justice system, emphasizing rehabilitation and community engagement.
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